When are actively balanced biphasic (‘Lilly’) stimulating pulses necessary in a neurological prosthesis? II pH changes; noxious products; electrode corrosion; discussion
When are actively balanced biphasic (‘Lilly’) stimulating pulses necessary in a neurological prosthesis? II pH changes; noxious products; electrode corrosion; discussion
复制标题
神经假体何时需要主动平衡双相（“Lilly”）刺激脉冲？ II 有毒产品的腐蚀；
DOI：
--
复制
发表时间：
2006
影响因子：
3.2
通讯作者：
P. Donaldson
中科院分区：
文献类型：
--
作者：
N. Donaldson;P. Donaldson
通常认为主动平衡（“Lilly”）刺激电流波形提供非常“安全”的刺激。虽然这是完全正确的，但神经假体中必要的波形发生器的规格要求额外的复杂性，并且可能还需要额外的费用和开发时间。本文及其配套文件询问是否使用简单的，被动电荷平衡的刺激脉冲是同样安全的，提供刺激参数和电路设计适当的照顾。它的结论是，在安全的可输送的电荷密度，在电极上的每个脉冲，释放有毒产品和刺激的有效性，简单的脉冲不需要给更差的性能，在某些情况下，他们可能会更好。
Actively balanced (‘Lilly’) stimulating current waveforms are generally considered to give very ‘safe’ stimulation. Although this is perfectly true, the specification of the necessary waveform generators in neurological prostheses demands additional complexity, and probably additional expense and development time as well. The paper and its companion enquire whether the use of simple, passively charged-balanced stimulating pulses is equally safe, provided the stimulation parameters and circuitry are designed with appropriate care. It is concluded that, in respect of safe deliverable charge density per pulse at the electrode, release of noxious products and stimulating effectiveness, simple pulses need give no worse performance; in some circumstances they may give better.