Calcium balance in 1-4-y-old children
Calcium balance in 1-4-y-old children
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DOI：
10.1093/ajcn/85.3.750
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发表时间：
2007-03-01
影响因子：
7.1
通讯作者：
Abrams, Steven A.
中科院分区：
文献类型：
--
作者：
Lynch, Mary Frances;Griffin, Ian J.;Abrams, Steven A.
背景资料：很少有钙平衡的数据是从幼儿的基础dietary recommendations.Objective：本研究的目的是评估之间的关系钙摄入量和平衡在健康的儿童年龄1-4 y消耗典型的美国dietes.Design：科目被分配到一个饮食与营养摄入量类似，他们的日常饮食。钙吸收采用双示踪稳定同位素技术进行评估。内源性粪便排泄量测定在一个子集的儿童，净钙balancedcalculated.Results：平均钙摄入量为551毫克/天（范围：124-983毫克/天），平均（+/- SEM）钙潴留为161 +/- 17毫克/天。平衡数据的线性和非线性建模都表明，钙摄入量约为470 mg/d导致钙潴留140 mg/d，这是满足该年龄段儿童预期骨骼生长需求的量。没有证据表明800至900 mg/d的钙摄入量达到了阈值摄入量，超过该阈值，钙潴留不会发生额外的增加。遵循美国饮食的1-4岁儿童的骨生长需要通过每日约470 mg/d的钙摄入量来满足，这表明目前500毫克/天的适当摄入量接近实际的估计平均需要量。在将这些摄入量作为饮食建议的基础之前，应在对照试验中评估与阈值一致的较高钙摄入量的益处和风险。
Background: Few calcium balance data are available from young children on which to base dietary recommendations.Objective: The objective of the study was to evaluate the relation between calcium intake and balance in healthy children aged 1-4 y consuming typical American diets.Design: Subjects were assigned to a diet with nutrient intakes similar to those of their usual diet. Calcium absorption was assessed by using a dual-tracer stable-isotope technique. Endogenous fecal excretion was measured in a subset of children, and net calcium balance was calculated.Results: Mean calcium intake was 551 mg/d (range: 124-983 mg/d), and mean (+/- SEM) calcium retention was 161 +/- 17 mg/d. Both linear and nonlinear modeling of balance data showed that a calcium intake of approximate to 470 mg/d led to calcium retention of 140 mg/d, which is the amount that meets expected bone growth needs in children of this age. No evidence was found that calcium intakes of 800 to 900 mg/d reached the threshold intake beyond which no additional increase in calcium retention would occur.Conclusions: Bone growth needs in 1-4-y-old children following American diets are met by a daily calcium intake of approximate to 470 mg/d, which suggests that the current Adequate Intake of 500 mg/d is close to the actual Estimated Average Requirement. The benefits and risks of higher calcium intakes consistent with threshold values should be evaluated in a controlled trial before those intakes could be used as a basis for dietary recommendations.