A Randomized Trial of a Low-Carbohydrate Diet vs Orlistat Plus a Low-Fat Diet for Weight Loss

A Randomized Trial of a Low-Carbohydrate Diet vs Orlistat Plus a Low-Fat Diet for Weight Loss
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DOI:
10.1001/archinternmed.2009.492
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发表时间:
2010-01-25
影响因子:
--
通讯作者:
Oddone, Eugene Z.
Oddone, Eugene Z.
中科院分区:
其他
文献类型:
--
作者:
Yancy, William S., Jr.;Westman, Eric C.;Oddone, Eugene Z.

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背景:两种有效的减肥疗法,低碳水化合物生酮饮食(LCKD)和奥利司他治疗结合低脂饮食(O + LFD),可供公众使用,但据我们所知,从未比较过。方法:来自北卡罗来纳州达勒姆市退伍军人事务部初级保健诊所的超重或肥胖门诊患者(n = 146)被随机分配到LCKD指导组(最初,
Background: Two potent weight loss therapies, a low-carbohydrate, ketogenic diet (LCKD) and orlistat therapy combined with a low-fat diet (O + LFD), are available to the public but, to our knowledge, have never been compared.Methods: Overweight or obese outpatients (n = 146) from the Department of Veterans Affairs primary care clinics in Durham, North Carolina, were randomized to either LCKD instruction (initially,