OPPORTUNISTIC NOSOCOMIAL MULTIPLY RESISTANT BACTERIAL-INFECTIONS - THEIR TREATMENT AND PREVENTION

OPPORTUNISTIC NOSOCOMIAL MULTIPLY RESISTANT BACTERIAL-INFECTIONS - THEIR TREATMENT AND PREVENTION
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DOI:
10.1093/jac/32.suppl_a.39
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发表时间:
1993-07-01
影响因子:
5.2
通讯作者:
JOLYGUILLOU, ML
JOLYGUILLOU, ML
中科院分区:
医学2区
文献类型:
--
作者:
BERGOGNEBEREZIN, E;DECRE, D;JOLYGUILLOU, ML

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处理医院感染的临床医生面临的最困难的问题之一是微生物耐药性。主要的医院感染(尿路感染、肺炎、败血症、手术伤口感染)涉及革兰氏阳性细菌、表皮葡萄球菌、耶克氏杆状杆菌耐药肠球菌以及新的多重耐药革兰氏阴性杆菌,如嗜麦芽黄单胞菌。人类不动杆菌和木糖酸不动杆菌。肺炎克雷伯菌和其他产生新型质粒介导β-内酰胺酶的肠杆菌科细菌的出现和传播,对第三代头孢菌素具有活性,增加了治疗院内感染的难度。
One of the most difficult problems confronting the clinician who deals with nosocomial infections is that of micobial resistance. The predominant nosocomial infections (urinary tract infections, pneumonia, septicaemia, surgical wound infections) involve increasing numbers of Gram-positive bacteria,Staphylococcus epidermidis, Corynebacterium jeikeiumor resistant enterococci as well as new multiresistant Gram-negative bacilli such asXanthomonas maltophilia. Acinetobacter baumanniiandAlcaligenes xylosoxydans. The emergence and spread ofKlebsiella pneumoniaeand other Enterobacteriaceae producing novel plasmid-mediatedβ-lactamases active against third-generation cephalosporins contribute to the difficulty in treating nosocomial infections.