National differences in publishing papers on adverse drug reactions.
National differences in publishing papers on adverse drug reactions.
复制标题
发表药物不良反应论文的国家差异。
DOI：
10.1111/j.1365-2125.2005.02267.x
复制
发表时间：
2005
影响因子：
3.4
通讯作者：
J. Aronson
中科院分区：
文献类型：
--
作者：
R. Ferner;J. Aronson
旨在
通过审查已发表的科学论文，研究各国对药物不良反应的态度如何不同。
方法
我们在奥维德EMBASE中检索了43个国家的按“治疗药物”类别和“不良反应”亚类别检索的出版物。
结果
我们统计了14年间全球1810202篇关于治疗药物的论文，其中195154篇（10.8%）被纳入不良反应子类别。各国之间存在巨大差异，无法用人口、经济差异、治疗药物的总体出版率或大型本土制药公司的存在来解释。
结论
许多当地文化因素影响了关于不良反应的论文占所有药物作用的比例，因此可能难以通过国际努力提高其认可度和报告率。
AIMS
To examine how countries differ in attitudes to adverse drug reactions by examining published scientific papers.
METHODS
We searched Ovid EMBASE for publications indexed by the category "therapeutic agents", and the subcategory "adverse effects", by country for 43 countries.
RESULTS
We counted 1 810 202 papers world-wide regarding therapeutic agents during 14 years, of which 195 154 (10.8%) were included in the adverse effects subcategory. There were substantial differences between countries, not explained by population, economic variation, overall publication rate on therapeutic agents, or the presence of large indigenous pharmaceutical companies.
CONCLUSIONS
Many local cultural factors influence the ratio of papers on adverse reactions to all drug effects, so it may be difficult to improve their recognition and reporting by international efforts.