Experimental gingivitis during pregnancy and post-partum: clinical, endocrinological, and microbiological aspects.
Experimental gingivitis during pregnancy and post-partum: clinical, endocrinological, and microbiological aspects.
复制标题
妊娠和产后实验性牙龈炎：临床、内分泌和微生物学方面。
DOI：
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发表时间：
1994
影响因子：
6.7
通讯作者：
L. Abraham
中科院分区：
文献类型：
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作者：
J. Raber;T. V. Steenbergen;U. Velden;J. Graaff;L. Abraham
这项研究的目的是评估在怀孕期间进行密集的口腔卫生方案是否会导致临床上健康的牙龈状态，并评估实验诱导的牙周炎在怀孕期间与产后相比是否在严重程度上有所不同。此外，还测定了龈下和口腔粘膜部位的黑色素革兰氏阴性厌氧菌水平，以及血浆中游离雌激素和前列腺素的浓度。这些参数在怀孕25周和产后6个月诱发的14天实验性牙周炎期间进行了研究。受试者被选在浅口袋或=4 mm，近端附着丧失不超过2 mm。由于控制了口腔卫生，孕期和产后的牙龈状况都有所改善。然而，在妊娠第0天，探诊时牙龈肿胀、发红和出血的发生率高于产后。在整个研究过程中，发现游离血浆雌激素和孕酮水平是正常的。有人推测，妊娠期间牙龈症状的严重程度的增加反映了这些激素水平增加的微血管生理效应。在妊娠期，实验性牙周炎在探诊时出现的肿胀、发红和出血比产后更多，而菌斑的数量在两个时期都是相似的。这表明牙菌斑堆积的结果是，牙周炎的发生叠加在妊娠相关的生理变化上。微生物学评价显示，孕期实验性牙周炎期间，中间普氏杆菌在龈下菌斑中的平均比例增加，而产后未发现这种微生物的增加。
The purpose of this study was to assess whether an intensive oral hygiene regimen practised during pregnancy results in a clinically healthy gingival state, and to assess whether experimentally-induced gingivitis differs in severity during pregnancy as compared to post-partum. In addition, levels of black-pigmented Gram negative anaerobes at subgingival and oral mucosal sites and plasma concentrations of free estrogens and prosterone were determined. These parameters were studied during a 14-day episode of experimental gingivitis induced in the 25th week of pregnancy, and again 6 months post-partum. The subjects were selected on shallow pockets < or = 4 mm and interproximal loss of attachment not exceeding 2 mm. As a result of controlled oral hygiene, the gingival condition improved both during pregnancy and post-partum. At day 0 during pregnancy, however, gingival swelling, redness, and bleeding on probing were found to be higher than post-partum. Free plasma levels of estrogens and progesterone were found to be normal throughout the study. It was hypothesized that the increase in severity of gingival symptoms during pregnancy reflect microvascular physiologic effects of increased levels of these hormones. During pregnancy, more swelling, redness and bleeding on probing developed during experimental gingivitis than post-partum, whereas the amount of plaque was similar in both phases. This suggests that as a result of dental plaque accumulation, gingival inflammation develops superimposed on pregnancy-associated physiologic alterations. Microbiological evaluation showed that the mean proportions of Prevotella intermedia in subgingival plaque increased during experimental gingivitis performed during pregnancy, whereas no increase of this micro-organism was found post-partum.
某些龈下微生物物种在选定牙周条件下的分布。
影响因子：
3.5
作者：
Savitt,ED;Socransky,SS
通讯作者：
Socransky,SS