Topographical micropatterning of poly(dimethylsiloxane) using laminar flows of liquids in capillaries
Topographical micropatterning of poly(dimethylsiloxane) using laminar flows of liquids in capillaries
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DOI：
10.1002/1521-4095(200104)13:8
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发表时间：
2001-04-18
影响因子：
29.4
通讯作者：
Whitesides, GM
中科院分区：
文献类型：
--
作者：
Takayama, S;Ostuni, E;Whitesides, GM
适合于研究活细胞在不同刺激下的行为的“微景观”是由聚二甲基硅氧烷浇铸而成的，方法是用Bu4Nf溶液同时蚀刻平板和浮雕(见图)，并用N-甲基吡咯烷酮冲洗溶解的物质。至关重要的是，蚀刻过程中的所有液体流都是层流的。文中给出了地貌的各种可达地形和应用实例。
"Micro-landscapes" suitable for investigating the behavior of living cells under different stimuli are cast from poly(dimethylsiloxane) by simultaneously etching a slab and a relief (see Figure) with a Bu4NF solution and flushing out dissolved material with N-methylpyrrolidone. It is crucial that all liquid streams during the etching process are laminar. Various accessible topographies for the relief and examples of applications are given.