SYMPATHETIC ACTIVITY IS INFLUENCED BY TASK-DIFFICULTY AND STRESS PERCEPTION DURING MENTAL CHALLENGE IN HUMANS
SYMPATHETIC ACTIVITY IS INFLUENCED BY TASK-DIFFICULTY AND STRESS PERCEPTION DURING MENTAL CHALLENGE IN HUMANS
复制标题
DOI：
10.1113/jphysiol.1992.sp019269
复制
发表时间：
1992-08-01
影响因子：
5.5
通讯作者：
SEALS, DR
中科院分区：
文献类型：
--
作者：
CALLISTER, R;SUWARNO, NO;SEALS, DR
1. 我们的目的是确定任务类型、任务的绝对和相对难度以及与任务执行相关的感知压力对人类认知挑战期间交感循环调节的影响。2。在改良的斯特鲁普色词测试 (CWT) 和心算 (MA) 过程中，连续记录了 12 名受试者通过腓骨显微神经造影确定的骨骼肌交感神经活动 (MSNA)、心率和动脉血压，每个受试者执行超过 6 个级别的绝对任务难度递增。评估每项任务的表现（正确百分比）并获得感知压力的评级。在相似的表现和感知压力水平下对 CWT 和 MA 的反应进行了比较。3． MSNA 在任务开始时下降，在不被认为有压力的低难度水平下保持在基线水平以下，在被认为有压力的较高难度水平下增加到基线水平以上，并在恢复期间进一步增加。因此，MSNA 的调节是应激依赖性的。在相似的压力感知水平下，CWT 和 MA 之间的 MSNA 没有差异。尽管随着任务难度的增加，表现会下降，但与 MSNA.4 刺激相关的表现并没有特定的“阈值”水平。在整个脑力任务中，动脉压和心率均高于基线水平。动脉压在每项任务的前 3-4 个级别中增加，然后趋于稳定，而心率在任务难度级别的增加中没有变化。 CWT 的心率和动脉压反应高于 MA.5。这些数据表明，在认知挑战期间，MSNA 的刺激主要受感知压力控制，而感知压力部分取决于任务难度的绝对水平。相比之下。认知任务的表现和类型似乎都不是 MSNA 的重要决定因素。动脉压受任务和难度的影响。心率与任务难度无关，但可能与任务相关。
1. Our aim was to determine the influence of the type of task, the absolute and relative difficulty of the task, and the perceived stress associated with performance of the task on sympathetic circulatory regulation during cognitive challenge in humans.2. Sympathetic nerve activity to skeletal muscle (MSNA) determined from peroneal microneurography, heart rate and arterial blood pressure were recorded continuously in twelve subjects during a modified Stroop colour word test (CWT) and mental arithmetic (MA), each performed over six levels of increasing absolute task difficulty. Performance (percentage correct) on each task was assessed and ratings of perceived stress obtained. Responses to CWT and MA were compared at similar levels of performance and perceived stress.3. MSNA decreased at task onset, remained below baseline levels at low levels of difficulty which were not perceived as stressful, increased above baseline levels at higher levels of difficulty which were perceived as stressful, and increased further during recovery. Thus, the regulation of MSNA was stress dependent. At similar levels of stress perception there were no differences in MSNA between CWT and MA. Although performance declined as task difficulty increased, there was no particular 'threshold' level of performance associated with the stimulation of MSNA.4. Arterial pressure and heart rate were elevated above baseline levels throughout the mental tasks. Arterial pressure increased over the first 3-4 levels of each task and then plateaued whereas heart rate did not vary across increasing levels of task difficulty. Heart rate and arterial pressure responses to CWT were higher than those to MA.5. These data demonstrate that during cognitive challenge the stimulation of MSNA is governed primarily by perceived stress which is dependent, in part, on the absolute level of task difficulty. In contrast. neither performance nor the type of cognitive task appear to be important determinants of MSNA. Arterial pressure is influenced by the task and level of difficulty. Heart rate is independent of task difficulty but may be task dependent.