Plant expansins: diversity and interactions with plant cell walls.
Plant expansins: diversity and interactions with plant cell walls.
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DOI：
10.1016/j.pbi.2015.05.014
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发表时间：
2015-06
影响因子：
9.5
通讯作者：
Cosgrove DJ
中科院分区：
文献类型：
--
作者：
Cosgrove DJ
扩展蛋白是二十年前发现的细胞壁蛋白，其通过催化植物细胞壁的松散而不裂解壁聚合物来介导酸诱导的生长。在此期间，我们的扩展蛋白的理解已经变得更加复杂，通过生物信息学分析扩展蛋白的分布和进化，以及通过表达分析，解剖上游转录因子调节表达，并通过序列和结构相似性识别其他类别的扩展蛋白。来自细菌的膨胀蛋白的分子分析已经确定了壁松弛活性所必需的残基，并澄清了膨胀蛋白结合复杂细胞壁的双功能性质。扩展蛋白表达的转基因调节改变植物的生长和胁迫生理，但并不总是以可预测的甚至可理解的方式。
Expansins were discovered two decades ago as cell wall proteins that mediate acid-induced growth by catalyzing loosening of plant cell walls without lysis of wall polymers. In the interim our understanding of expansins has gotten more complex through bioinformatic analysis of expansin distribution and evolution, as well as through expression analysis, dissection of the upstream transcription factors regulating expression, and identification of additional classes of expansin by sequence and structural similarities. Molecular analyses of expansins from bacteria have identified residues essential for wall loosening activity and clarified the bifunctional nature of expansin binding to complex cell walls. Transgenic modulation of expansin expression modifies growth and stress physiology of plants, but not always in predictable and even understandable ways.