Intra-venous digital subtraction angiography: an alternative method to intra-arterial digital subtraction angiography for experimental aneurysm imaging
Intra-venous digital subtraction angiography: an alternative method to intra-arterial digital subtraction angiography for experimental aneurysm imaging
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DOI：
10.1007/s00234-005-1425-1
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发表时间：
2005-10-01
期刊：
影响因子：
2.8
通讯作者：
Kallmes, DF
中科院分区：
文献类型：
--
作者：
Ding, YH;Dai, DY;Kallmes, DF
传统的动脉内数字减影血管造影术(IADSA)需要手术暴露和结扎股动脉，是一种有创且昂贵的评估兔实验性弹力酶诱导的动脉瘤的方法。本研究的目的是检查和验证静脉内数字减影血管造影术(IVDSA)作为IADSA的替代方法，比较它们的诊断准确性。我们在一个兔模型中对24个弹力酶诱导的囊状动脉瘤同时进行了IVDSA和IADSA检查，动脉瘤形成后1个月。评估和测量来自IVDSA和IADSA手术的动脉瘤大小(颈部、宽度和高度)。采用Wilcoxon配对符号列检验比较IVDSA和IADSA的动脉瘤大小。所有动脉瘤在IVDSA和IADSA技术上均清晰显示。平均瘤颈、瘤宽、瘤高分别为3.41±0.80 mm、3.61±0.93 mm、8.07±2.11 mm。颈、宽、高的平均直径分别为3.43±0.80 mm、3.66±0.92 mm和8.16±2.25 mm。两组瘤颈大小、瘤宽、瘤高差异无统计学意义(分别为P=0.311、P=0.086和P=0.258)。IVDSA似乎是评估弹性酶诱导的兔动脉瘤的一种替代方法。
Conventional intra-arterial digital subtraction angiography (IADSA), which necessitates surgical exposure and ligation of the femoral artery, is an invasive and expensive method of evaluation for experimental elastase-induced aneurysms in rabbits. The purpose of this study was to examine and validate intra-venous digital subtraction angiography (IVDSA) as an alternative to IADSA by comparing their diagnostic accuracies. We performed both IVDSA and IADSA for 24 elastase-induced saccular aneurysms in a rabbit model, 1 month following creation. Aneurysm sizes (neck, width and height) from both the IVDSA and IADSA procedures were evaluated and measured. Comparison of the aneurysm sizes between IVDSA and IADSA were performed with the Wilcoxon paired signed-rank test. All the aneurysms were seen clearly in both the IVDSA and IADSA techniques. Mean sizes of the IVDSA aneurysm neck, width and height were 3.41 +/- 0.80 mm, 3.61 +/- 0.93 mm and 8.07 +/- 2.11 mm, respectively. Mean sizes of the IADSA aneurysm neck, width and height were 3.43 +/- 0.80 mm, 3.66 +/- 0.92 mm and 8.16 +/- 2.25 mm, respectively. No significant difference was found in the sizes of the aneurysm neck, width and height between the two groups (P=0.311, P=0.086 and P=0.258, respectively). IVDSA appears to be an alternative method for evaluating elastase-induced aneurysms in rabbits.