Introduction and Discovery of Retinitis Pigmentosa.
Introduction and Discovery of Retinitis Pigmentosa.
复制标题
色素性视网膜炎的介绍和发现。
DOI：
10.1007/978-1-0716-2651-1_1
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Wang,Nan-Kai
中科院分区：
文献类型：
--
作者：
Wang,Hung-Hsi;Chen,Nelson;Wang,Nan-Kai
视网膜色素变性（RP）是最常见的遗传性视网膜营养不良。RP有三个主要特征：夜盲、视网膜色素沉着和视野收缩。在这三个特征中，夜盲症是最早被发现的，可以追溯到公元前1500年左右的古埃及人。然而，当时描述的夜盲症最有可能与维生素A缺乏有关，而不是RP。在检眼镜发明之前，视网膜色素变性首先在尸体解剖中被描述。然而，它与RP或夜盲症无关。直到检眼镜的发明，眼科医生才能真正观察眼睛，并将视网膜色素沉着与临床症状联系起来，如夜盲症和视野收缩。1983年，在一次聚集了许多专家的RP研讨会上，就RP诊断的术语和指南达成了共识。本章将沿着介绍快速成型技术的发展历史、发现过程及其特点。
Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy. There are three main characteristics of RP: night blindness, retinal pigmentation, and visual field constriction. Among these three features, night blindness was the first to be discovered, which could be dated back to the ancient Egyptians at around 1500 BC. However, the night blindness described at that time was most likely associated with vitamin A deficiency rather than RP. Retinitis pigmentosa was first described in cadaver anatomic dissection before the invention of the ophthalmoscope. However, it was not linked to RP or night blindness. It was not until the invention of the ophthalmoscope that ophthalmologists could truly look into the eye and correlate the retinal pigmentation with clinical symptoms, such as night blindness and visual field constriction. In 1983, at a RP workshop that gathered together many experts, a consensus was reached regarding the terminology and guidelines for the diagnosis of RP. In this chapter, we will introduce the history and discovery of RP along with its characteristics.