Antibacterial activities of a few prepared derivatives of oleanolic acid and of other natural triterpenic compounds

Antibacterial activities of a few prepared derivatives of oleanolic acid and of other natural triterpenic compounds
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DOI:
10.1016/s1631-0748(03)00066-3
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发表时间:
2003-04-01
影响因子:
1.6
通讯作者:
Mighri, Z
Mighri, Z
中科院分区:
化学4区
文献类型:
--
作者:
Hichri, F;Ben Jannet, H;Mighri, Z

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氧化已经制备了油酸1的磷、酯和酰胺衍生物。以Tween-80为络合剂,研究了从萝摩科杠柳果皮中分离得到的化合物1及其衍生物的抑菌活性。山楂酸乙酸酯2、β-香树素3及其乙酰化衍生物3a具有相同的活性(图1)。也研究了从与油酸1相同的来源中分离的化合物。(C)2003年科学院。出版社:editions scientifiques et medicales Elsevier SAS。All rights reserved.
Oxidizing. phosphorus, ester and amide derivatives of oleanolic acid 1 have been prepared. The antibacterial activity of compound 1, isolated from the fruit barks of Periploca laevigata (Asclepiadaceae), and its derivatives have been tested using Tween-80 as complex agent to form a water-soluble triterpenes. The same activity of maslinic acid acetate 2, beta-amyrin 3, and its acetylated derivative 3a (Fig. 1). isolated from the same source as that of oleanolic acid 1, have also been investigated. (C) 2003 Academie des sciences. Published by editions scientifiques et medicales Elsevier SAS. All rights reserved.