High risks of HIV transmission for men who have sex with men--a comparison of risk factors of HIV infection among MSM associated with recruitment channels in 15 cities of China.
High risks of HIV transmission for men who have sex with men--a comparison of risk factors of HIV infection among MSM associated with recruitment channels in 15 cities of China.
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DOI：
10.1371/journal.pone.0121267
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Sun J
中科院分区：
文献类型：
--
作者：
Qi J;Zhang D;Fu X;Li C;Meng S;Dai M;Liu H;Sun J
尽管中国各地艾滋病流行情况因地区和人群而异，但男男性行为者（MSM）的艾滋病发病率继续以惊人的速度上升。本研究旨在分析中国大城市不同渠道招募的男男性接触者感染HIV的危险因素，为制定有针对性的干预策略提供参考。2011年7月至12月，共招募了来自14个城市和1个省的33，684名男男性行为者。使用信息收集卡收集人口统计学（如年龄、婚姻状况、教育）和行为（如安全套使用、HIV检测史）数据。还收集了血液样本，以检测艾滋病毒和梅毒。参与者是从五个不同的渠道招募的，他们都表现出不同的特点。HIV筛查阳性率为6.27%，梅毒感染率为6.50%。从公共浴室招募的人群中HIV和梅毒感染率最高，分别为11.80%和11.20%。梅毒感染者的HIV阳性筛查率最高（13.75%; 95%CI OR，2.33-3.06）。生活在这个国家的西南地区（11.64%; OR=2.76，95%CI OR 2.19-3.47），年龄>20岁（P<0.001），居住在我国西南地区（OR=2.76，95%CI 2.19-3.47），过去3个月内未与女性发生性关系（OR=1.27，95%CI 1.09-1.48）、最近一次肛交时未使用安全套（OR=1.54，95%CI 1.39-1.70）等因素均与HIV检测结果阳性的概率较高相关。根据他们的招募方式，需要更有针对性的干预措施，以防止艾滋病毒/艾滋病在不同特征和行为的男男性行为者中传播。本研究结果可为研究者进一步研究和政策制定者制定更有效的干预策略提供依据。
While the HIV epidemic varies greatly by region and population group throughout China, the HIV incidence among men who have sex with men (MSM) continues to rise at an alarmingly fast pace. We seek to analyze the risk factors associated with HIV infection among MSM recruited from different channels in large urban centers across China, in an attempt to shed light on the design of future targeted intervention strategies. A total of 33,684 MSM from 14 cities and one province were recruited from July to December 2011. Demographic (e.g. age, marital status, education) and behavioral (e.g. condom use, HIV testing history) data were collected using information collection cards. Blood samples were also collected to test for HIV and Syphilis. Participants were recruited from five different channels, and all demonstrated distinct characteristics. The overall rate of positive HIV screening was 6.27% and the rate of syphilis infection was 6.50%. Participants recruited from bathhouses had the highest HIV (11.80%) and syphilis infection rates (11.20%). Participants who were infected with syphilis had the highest HIV-positive screening rate (13.75%; 95% CI OR, 2.33-3.06). living in the southwest region of the country (11.64%; OR=2.76, 95%CI OR 2.19-3.47), Being >20 years of age (P<0.001), living in the southwest region of the country (OR=2.76, 95%CI 2.19-3.47), not having sex with female over the previous 3 months (OR=1.27, 95%CI 1.09-1.48), no condom use during the last anal intercourse (OR=1.54, 95%CI 1.39-1.70) and other factors were all associated with a higher probability of having an HIV-positive test result. Depending on the way they are recruited, more targeted interventions are required to prevent the spread of HIV/AIDS among MSM with different characteristics and behaviors. Results from this study could provide evidence for researchers to conduct further studies and policy-makers to establish more effective and strategic interventions for MSM in China.
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