Evolution of a polyphenism by genetic accommodation
Evolution of a polyphenism by genetic accommodation
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DOI：
10.1126/science.1118888
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发表时间：
2006-02-03
期刊：
影响因子：
56.9
通讯作者：
Nijhout, HF
中科院分区：
文献类型：
--
作者：
Suzuki, Y;Nijhout, HF
多型性是指一个基因组在不同的环境中与离散的替代表型相关联的适应性。关于多型现象起源的机制知之甚少。我们发现，在青少年的发育调节途径中的突变，使热应激揭示了一个隐藏的反应规范的幼虫着色。选择增加颜色变化的热应激导致的幼虫的颜色多型性和相应的变化，通过遗传调节激素滴度的演变。显然，调节发育激素的机制可以掩盖遗传变异，并作为进化电容器，促进新的适应性表型的起源。
Polyphenisms are adaptations in which a genome is associated with discrete alternative phenotypes in different environments. Little is known about the mechanism by which polyphenisms originate. We show that a mutation in the juvenile hormone-regulatory pathway in Manduca sexta enables heat stress to reveal a hidden reaction norm of larval coloration. Selection for increased color change in response to heat stress resulted in the evolution of a larval color polyphenism and a corresponding change in hormonal titers through genetic accommodation. Evidently, mechanisms that regulate developmental hormones can mask genetic variation and act as evolutionary capacitors, facilitating the origin of novel adaptive phenotypes.