Mouse Models of Cardiac Arrhythmias.
Mouse Models of Cardiac Arrhythmias.
复制标题
DOI：
10.1161/circresaha.118.313406
复制
发表时间：
2018-07-20
影响因子：
20.1
通讯作者：
Wehrens XHT
中科院分区：
文献类型：
--
作者：
Dobrev D;Wehrens XHT
小鼠模型对于描述特定基因和信号通路对心律失常发病机制的贡献具有不可估量的价值。考虑到小鼠和人类之间存在重要差异，我们在此讨论小鼠心律失常模型的优点和局限性。
Mouse models have been invaluable for delineating the contributions of specific genes and signaling pathways to the pathogenesis of cardiac arrhythmias. Considering that there are important differences between mice and humans, here we discuss the strengths and limitations of mouse models of cardiac arrhythmias.