RETINAL SENSITIVITY TO DAMAGE FROM SHORT WAVELENGTH LIGHT
RETINAL SENSITIVITY TO DAMAGE FROM SHORT WAVELENGTH LIGHT
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DOI：
10.1038/260153a0
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发表时间：
1976-01-01
期刊：
影响因子：
64.8
通讯作者：
SLINEY, DH
中科院分区：
文献类型：
--
作者：
HAM, WT;MUELLER, HA;SLINEY, DH
越来越多的文献证明了长期暴露在光下的有害影响1 -8。为了更严格地定义热效应和光化学效应之间的差异，我们将恒河猴的视网膜暴露于1，064 -441.6 nm的八条单色激光线。对于1，064-nm线，预期对视网膜的热损伤，因为不涉及色素沉着，并且能量吸收主要发生在色素上皮和脉络膜的黑色素颗粒中。虽然关于发病机制的数据还没有，但我们发现了一些有趣的差异，从近红外到可见光谱中的蓝色波长的视网膜敏感性。
A GROWING body of literature attests to the deleterious effects of long term exposure to light1–8. To define more critically the differences between thermal and photochemical effects, we have exposed the retinae of rhesus monkeys to eight monochromatic laser lines from 1,064–441.6 nm. Thermal damage to the retina is to be expected for the 1,064-nm line since the photopigments are not involved and energy absorption takes place predominantly in the melanin granules of the pigment epithelium and the choroid. Although data on pathogenesis are not yet available, we found some interesting differences in retinal sensitivity in going from the near infrared to the blue wavelengths in the visible spectrum.