DNA Translocation through Graphene Nanopores
DNA Translocation through Graphene Nanopores
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DOI：
10.1021/nl101046t
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发表时间：
2010-08-01
期刊：
影响因子：
10.8
通讯作者：
Drndic, Marija
中科院分区：
文献类型：
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作者：
Merchant, Christopher A.;Healy, Ken;Drndic, Marija
我们报告通过石墨烯膜中创建的纳米孔的DNA易位。设备由1-5纳米厚的石墨烯膜组成，具有直径5至10纳米的电子束雕刻纳米孔。由于石墨烯膜的薄性质，我们观察到比传统固态纳米孔更大的阻塞电流。然而，离子电流噪声水平比氮化硅纳米孔的离子电流噪声水平大几个数量级。这些波动减少了15纳米的二氧化钛的原子层沉积在设备上。与绝缘的传统固态纳米孔材料不同，石墨烯是一种优良的电导体。使用石墨烯作为膜材料为一类新的纳米孔器件打开了大门，其中电子传感和控制直接在孔处进行。
We report on DNA translocations through nanopores created in graphene membranes. Devices consist of 1-5 nm thick graphene membranes with electron-beam sculpted nanopores from 5 to 10 nm in diameter. Due to the thin nature of the graphene membranes, we observe larger blocked currents than for traditional solid-state nanopores. However, ionic current noise levels are several orders of magnitude larger than those for silicon nitride nanopores. These fluctuations are reduced with the atomic-layer deposition of 15 nm of titanium dioxide over the device. Unlike traditional solid-state nanopore materials that are insulating, graphene is an excellent electrical conductor. Use of graphene as a membrane material opens the door to a new class of nanopore devices in which electronic sensing and control are performed directly at the pore.