Outcomes of Subaortic Obstruction Resection in Children
Outcomes of Subaortic Obstruction Resection in Children
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DOI：
10.1016/j.hlc.2016.05.120
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发表时间：
2017-02-01
影响因子：
2.6
通讯作者：
Konstantinov, Igor E.
中科院分区：
文献类型：
--
作者：
Donald, Julia S.;Naimo, Phillip S.;Konstantinov, Igor E.
背景：关于离散性主动脉瓣下狭窄的长期结局的研究很少。因此，我们回顾了单一机构26年来纤维肌肉切除术治疗儿童主动脉瓣下狭窄的远期疗效。方法对至2015年间收治的72例因离散性主动脉瓣下狭窄而行主动脉瓣下梗阻切除术的儿童进行回顾性分析。无手术死亡，晚期死亡3例(4.2%，3/72)。10年Kaplan-Meier生存率为93.0+/-3.9%(95%可信区间：79.6，97.7)。左室流出道瞬时峰值多普勒压差由术前74.2+/-36.7毫米汞柱(16.0~242.0毫米汞柱)降至12.8±7.4毫米汞柱(2.6~36.0毫米汞)(P<0.05)。
Background Studies of long-term outcomes of discrete subaortic stenosis are rare. Therefore, we reviewed the long-term outcomes of fibromuscular resection in children with subaortic stenosis over 26 years from a single institution.Methods We conducted a retrospective review of all children (n=72) who underwent resection of subaortic obstruction for discrete subaortic stenosis between 1989 and 2015.Results Median age at surgery was 5.0 years (2.7-7.6 years). There were no operative deaths but three late deaths (4.2%, 3/72). Overall Kaplan-Meier survival at 10 years was 93.0 +/- 3.9% (95% CI: 79.6, 97.7). Peak instantaneous left ventricular outflow tract Doppler gradient decreased from 74.2 +/- 36.7 mmHg (16.0-242.0 mmHg) preoperatively to 12.8 +/- 7.4 mmHg (2.6-36.0 mmHg) postoperatively (p