Sensitivity enhancement in photonic crystal slab biosensors
Sensitivity enhancement in photonic crystal slab biosensors
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DOI：
10.1364/oe.18.022702
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发表时间：
2010-10-25
期刊：
影响因子：
3.8
通讯作者：
Levi, Ofer
中科院分区：
文献类型：
--
作者：
El Beheiry, Mohamed;Liu, Victor;Levi, Ofer
分析了光子晶体板中导频共振的折射率敏感性。我们发现，模态属性的引导共振强烈影响光谱灵敏度和品质因数，导致折射率灵敏度的大幅提高。一个三倍的光谱灵敏度增强被证明为悬浮板的设计，与基板上休息的板的设计相比。光谱灵敏度值还示出不受品质因数降低的影响，这是常见的制造光子晶体纳米结构。最后，我们确定，适当选择光子晶体板的设计参数允许生物传感的分析物，包括蛋白质，抗原和细胞的范围很广。这些光子晶体与大面积生物传感器设计兼容，允许直接访问微流体装置中的外部入射光束。(C)2010年美国光学学会
Refractive index sensitivity of guided resonances in photonic crystal slabs is analyzed. We show that modal properties of guided resonances strongly affect spectral sensitivity and quality factors, resulting in substantial enhancement of refractive index sensitivity. A three-fold spectral sensitivity enhancement is demonstrated for suspended slab designs, in contrast to designs with a slab resting over a substrate. Spectral sensitivity values are additionally shown to be unaffected by quality factor reductions, which are common to fabricated photonic crystal nanostructures. Finally, we determine that proper selection of photonic crystal slab design parameters permits biosensing of a wide range of analytes, including proteins, antigens, and cells. These photonic crystals are compatible with large-area biosensor designs, permitting direct access to externally incident optical beams in a microfluidic device. (C) 2010 Optical Society of America