Migraine frequency and health utilities: Findings from a multisite survey
Migraine frequency and health utilities: Findings from a multisite survey
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DOI：
10.1111/j.1524-4733.2007.00246.x
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发表时间：
2008-03-01
期刊：
影响因子：
4.5
通讯作者：
Menzin, Joseph
中科院分区：
文献类型：
--
作者：
Brown, Jeffrey S.;Neumann, Peter J.;Menzin, Joseph
目的：评估偏头痛频率与健康效用之间的关系。方法：年龄>= 18岁、诊断为阵发性偏头痛的患者在代表不同医疗保健提供模式的三个美国研究中心入组。所有受试者都完成了一份问卷，其中包括人口统计学和临床信息，偏头痛特异性残疾问卷和健康实用指数3（HUI 3）。HUI 3是一种通用的健康状况和健康相关的生活质量指标。HUI 3健康状态数据被转换为效用评分，锚定0（死亡）和1（完美健康）。平均年龄为44岁，87%为女性。平均（+/- SD）每月偏头痛频率为4.4 +/- 3.6，34%报告每月6次偏头痛。平均（+/- SD）HUI 3评分为0.62 +/- 0.26。在控制了研究中心、人口统计学、合并症、偏头痛特征和偏头痛干扰水平后，发现偏头痛频率与HUI 3评分显著（P < 0.05）负相关。每月偏头痛> 6次的受试者的调整后平均HUI 3评分为0.41;
Objective: Assess the relationship between migraine frequency and health utility.Methods: Patients aged >= 18 years diagnosed with episodic migraine were enrolled at three US sites representing varied models of health-care delivery. All subjects completed a questionnaire that included demographic and clinical information, a migraine-specific disability questionnaire, and the Health Utilities Index Mark 3 (HUI3). The HUI3 is a generic health status and health-related quality-of-life measure. HUI3 health status data are translated into utility scores anchored by 0 (dead) and 1 (perfect health).Results: The study enrolled 150 patients. The mean age was 44 years and 87% were female. Mean (+/- SD) monthly migraine frequency was 4.4 +/- 3.6, with 34% reporting 6 migraines per month. The mean (+/- SD) HUI3 score was 0.62 +/- 0.26. After controlling for study center, demographics, comorbidities, migraine characteristics, and level of migraine disruptiveness, migraine frequency was found to be significantly (P < 0.05) and negatively associated with HUI3 scores. Subjects with > 6 migraines per month had an adjusted mean HUI3 score of 0.41; the corresponding mean for those reporting