Assessment of left atrial ejection force in hypertrophic cardiomyopathy using real-time three-dimensional echocardiography
Assessment of left atrial ejection force in hypertrophic cardiomyopathy using real-time three-dimensional echocardiography
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DOI：
10.1016/j.echo.2006.11.017
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发表时间：
2007-06-01
影响因子：
6.5
通讯作者：
ten Cate, Folkert J.
中科院分区：
文献类型：
--
作者：
Anwar, Ashraf M.;Soliman, Osama I. I.;ten Cate, Folkert J.
该研究包括30例肥厚型心肌病（HCM）患者（梗阻性和非梗阻性）和15名对照组。实时三维超声心动图测量舒张末期二尖瓣环面积（MAA（3D））和二尖瓣面积（MVA 3D）。应用二维超声心动图测量二尖瓣口面积（MVA）、二维（2D）及二尖瓣口流入道峰值A波速度（V）。通过二维超声心动图和实时三维超声心动图计算左心房射血力（LA-EF），公式为：0.5 X 1.06 X（MAA或MVA）X V-2，其中（1.06）为血液粘度。HCM患者的LA-EF 2D-MVA、LA-EF 3D-MVA、LA-EF 3D-MAA和V显著高于对照组（P <0.001）。HCM组LA-FF 2D-MVA和LA-EF 3D-MVA均低于LA-EF 3D-MAA（P <0.001）。梗阻性HCM患者LA-EF 2D-MVA、LA-EF 2D-MVA、LA-EF 3D-MAA和V显著高于非梗阻性HCM患者（P <0.05）。梗阻性肥厚型心肌病患者左室流出道压差与高左室射血分数无关。我们得出结论，HCM与LA、EF高于正常相关，梗阻性HCM高于非梗阻性HCM，表明LA-EF 3D-MAA反映了更高的心房工作负荷。
The study included 30 patients with hypertrophic cardiomyopathy (HCM) (obstructive and nonobstructive) and 15 control subjects. End-diastolic mitral annulus area (MAA(3D)) and mitral valve area (MVA3D) were measured by real-time 3-dimensional (3D) echocardiography. MVA,2D and peak mitral inflow A wave velocity (V) were measured by 2-dimensional (2D) echocardiography. Left atrial ejection force (LA-EF) was calculated by 2D echocardiography and real-time 3D echocardiography using the formula: 0.5 X 1.06 X (MAA or MVA) X V-2, where (1.06) is blood viscosity. LA-EF2D-MVA, LA-EF3D-MVA, LA-EF3D-MAA, and V were significantly higher in patients with HCM than control subjects (P < .001). LA-FF2D-MVA and LA-EF3D-MVA were lower than LA-EF3D-MAA in HCM only (P < .001). In obstructive HCM, LA-EF2D-MVA, LA-EF2D-MVA, LA-EF3D-MAA, and V were significantly higher than in nonobstructive HCM (P < .05). Left ventricular outflow tract gradient contributed independently to high LA-EF in obstructive HCM. We concluded that HCM is associated with higher LA, EF than normal, and higher in obstructive HCM than nonobstructive indicating a higher atrial workload that is reflected by LA-EF3D-MAA.