Design and baseline characteristics of a population-based study of eye disease in southern Chinese people: the Dongguan Eye Study

Design and baseline characteristics of a population-based study of eye disease in southern Chinese people: the Dongguan Eye Study
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DOI:
10.1111/ceo.12670
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发表时间:
2016-04-01
影响因子:
4
通讯作者:
Guo, Haike
Guo, Haike
中科院分区:
医学2区
文献类型:
--
作者:
Meng, Qianli;Cui, Ying;Guo, Haike

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背景描述东莞眼科研究的设计、方法和基线特征。设计基于人群的横断面研究。方法东莞眼科研究于2011年9月至2012年2月在东莞横沥进行,共调查了8952名40岁以上的农村居民。访谈内容包括人口统计数据、社会经济状况以及与健康和视力有关的生活质量。体格测量包括身高、体重、腰围和臀围、心率和血压。实验室检查包括空腹血糖、血红蛋白A1 c、口服葡萄糖耐量、血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、血清肌酐、血尿素氮和尿酸。眼科检查包括视力和自动屈光测试,眼压测量,裂隙灯检查,眼生物测量,前房角镜检查,眼底照相,视网膜神经纤维层成像和视野testing.Main Outcome MeasuresPrevalence和危险因素的视力损害,失明,眼部疾病及其关联系统的医疗指标或健康相关的生活方式,以及糖尿病受试者的流行病学数据。方法,应答率和基线特征presented.ResultsOf 11357个人符合东莞眼科研究,8952(78.82%)的主题参加。所有参与者都是自认为是汉族人。平均年龄54.0岁,女性占59.9%,农民占48.4%,小学、初中文化程度占77.2%。平均体重指数和腰臀比分别为24.63.9kg/m2和0.9 ± 0.2。结论东莞市眼科研究的数据提供了有关中国南方城市化过程中农村居民眼病患病率、危险因素和影响的信息。
BackgroundTo describe the study design, methodology and baseline characteristics of the Dongguan Eye Study.DesignPopulation-based, cross-sectional studyParticipantsA total of 8952 rural-dwelling residents aged 40years or older in Hengli, Dongguan.MethodsThe Dongguan Eye Study was conducted from September 2011 to February 2012. The interview covered demographic data, socio-economic status and health- and vision-related quality of life. Physical measurements included height, weight, waist and hip circumference, heart rate and blood pressure. Laboratory tests included fasting blood glucose, haemoglobin A1c, oral glucose tolerance, serum total cholesterol, triglycerides, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, serum creatinine, blood urea nitrogen and uric acid. Ophthalmic examinations included visual acuity and autorefraction testing, intraocular pressure measurement, slit-lamp examination, ocular biometry, gonioscopy, fundus photography, retinal nerve fibre layer imaging and visual field testing.Main Outcome MeasuresPrevalence and risk factors for visual impairment, blindness, eye diseases and their associations with systemic medical indicators or health-related lifestyles, as well as epidemiological data on diabetic subjects. Methodology, response rates and baseline characteristics are presented.ResultsOf the 11357 individuals eligible for the Dongguan Eye Study, 8952 (78.82%) subjects participated. All participants were self-identified Han Chinese. The average age was 54.0years, 59.9% were female, 48.4% were farmers and 77.2% had elementary or junior middle school educational levels. The average body mass index and waist-hip ratio were 24.63.9kg/m(2) and 0.9 +/- 0.2.ConclusionsData from the Dongguan Eye Study provide information concerning the prevalence, risk factors and impacts of eye diseases in rural residents undergoing urbanization in southern China.