Titanium-Based Biomaterials for Preventing Stress Shielding between Implant Devices and Bone.
Titanium-Based Biomaterials for Preventing Stress Shielding between Implant Devices and Bone.
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DOI：
10.1155/2011/836587
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发表时间：
2011
影响因子：
3.1
通讯作者：
Nakai M
中科院分区：
文献类型：
--
作者：
Niinomi M;Nakai M
对于用于替代失效硬组织的植入物，需要具有低杨氏模量的β型钛合金来抑制骨萎缩并增强骨重建。同时，要求这些钛合金具有较高的静强度和动强度。另一方面，需要具有可变杨氏模量的金属生物材料来满足患者和外科医生的需求，即分别为低杨氏模量和高杨氏模量。本文讨论了提高生物医学应用中β型钛合金静态和动态强度同时保持低杨氏模量的有效方法。从抑制骨萎缩和促进骨重建的角度讨论了低杨氏模量β型钛合金在生物医学应用中的优势。此外，我们还讨论了用于可移除植入物的具有自调节杨氏模量的β型钛合金的开发。
β-type titanium alloys with low Young's modulus are required to inhibit bone atrophy and enhance bone remodeling for implants used to substitute failed hard tissue. At the same time, these titanium alloys are required to have high static and dynamic strength. On the other hand, metallic biomaterials with variable Young's modulus are required to satisfy the needs of both patients and surgeons, namely, low and high Young's moduli, respectively. In this paper, we have discussed effective methods to improve the static and dynamic strength while maintaining low Young's modulus for β-type titanium alloys used in biomedical applications. Then, the advantage of low Young's modulus of β-type titanium alloys in biomedical applications has been discussed from the perspective of inhibiting bone atrophy and enhancing bone remodeling. Further, we have discussed the development of β-type titanium alloys with a self-adjusting Young's modulus for use in removable implants.