Urease operon and urease activity in commensal and disease-causing nontypeable Haemophilus influenzae.

Urease operon and urease activity in commensal and disease-causing nontypeable Haemophilus influenzae.
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共生和致病的不可分型流感嗜血杆菌中的脲酶操纵子和脲酶活性。

DOI:
10.1128/jcm.03145-12
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发表时间:
2013
影响因子:
9.4
通讯作者:
Gilsdorf,JanetR
Gilsdorf,JanetR
中科院分区:
医学2区
文献类型:
--
作者:
Zhang,Lixin;Patel,Mayuri;Xie,Jingping;Davis,GreggS;Marrs,CarlF;Gilsdorf,JanetR

文献摘要

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在引起中耳炎和慢性阻塞性肺疾病(COPD)相关性支气管炎的流感嗜血杆菌分离株中,Theureoperon的检出率明显高于健康人(97%vs78.1%,P < 0.001)。缺乏脲操纵子的菌株来自咽喉的可能性是中耳炎或COPD菌株的8倍以上。
Theureoperon was significantly more prevalent in Haemophilus influenzae isolates causing otitis media and chronic obstructive pulmonary disease (COPD)-associated bronchitis than in those from throats of healthy individuals (97% versus 78.1%,P< 0.001). Strains lacking theureoperon are over 8 times more likely to be from the throat than either otitis media or COPD isolates.