Beating heart mitral valve replacement with a bovine pericardial bioprosthesis for treatment of mitral valve dysplasia in a Bull Terrier.
Beating heart mitral valve replacement with a bovine pericardial bioprosthesis for treatment of mitral valve dysplasia in a Bull Terrier.
复制标题
用牛心包生物假体进行心脏二尖瓣置换术治疗牛头梗二尖瓣发育不良。
作者：
L. Behr;V. Chetboul;C. C. Sampedrano;Goun Vassiliki;J. Pouchelon;F. Laborde;N. Borenstein
目标
描述一种开放的心脏不停跳外科技术和牛心包人工瓣膜在犬二尖瓣置换术(MVR)中的应用。
研究设计
临床病例报告。
动物
公牛梗(17个月大，26公斤)，伴有二尖瓣发育不良和严重的反流。
方法
采用体外循环心脏不停跳心内直视手术技术，用牛心包生物瓣替代二尖瓣。
结果
成功的MVR是使用心脏跳动技术实现的。二尖瓣反流缓解，心功能改善(左心室舒张末内径由57.6 mm降至48.7 mm，左房/主动脉比值由1.62降至1.19)。与标准的心脏停搏技术相比，体外循环时间和手术总时间明显缩短。手术恢复顺利，6个月后超声心动图显示瓣膜功能良好。
结论
考虑到技术优势(不需要心脏骤停、缺血再灌注损伤和低温，也不需要主动脉夹层和插管来注射心脏停搏液)，与标准的心脏停搏技术相比，短期死亡率和发病率可能会降低。
临床相关性
根据这只狗的经验，心脏跳动中的二尖瓣置换术似乎是一种安全可行的选择，牛心包假体可能比机械假体提供更好的长期存活率。
OBJECTIVES
To describe an open, beating heart surgical technique and use of a bovine pericardial prosthetic valve for mitral valve replacement (MVR) in the dog.
STUDY DESIGN
Clinical case report.
ANIMALS
Male Bull Terrier (17-month-old, 26 kg) with mitral valve dysplasia and severe regurgitation.
METHODS
A bovine pericardial bioprosthesis was used to replace the mitral valve using an open beating heart surgical technique and cardiopulmonary bypass.
RESULTS
Successful MVR was achieved using a beating heart technique. Mitral regurgitation resolved and cardiac performances improved (left ventricular end-diastolic diameter decreased from 57.6 to 48.7 mm, and left atrium/aorta ratio returned to almost normal, from 1.62 to 1.19). Cardiopulmonary by-pass time and total surgical duration were decreased compared with standard cardioplegic techniques. Surgical recovery was uneventful and on echocardiography 6 months later valve function was excellent.
CONCLUSION
Considering the technique advantages (no cardiac arrest, ischemic reperfusion injury, and hypothermia, or the need for aortic dissection and cannulation for administration of cardioplegic solution), short-term mortality and morbidity may be reduced compared with standard cardioplegic techniques.
CLINICAL RELEVANCE
Based on experience in this dog, beating heart mitral valvular replacement is a seemingly safe and viable option for the dog and bovine pericardial prosthesis may provide better long-term survival than mechanical prostheses.
影响因子：
4.6
作者：
Nelson, DP;Wechsler, SB;Neufeld, EJ
通讯作者：
Neufeld, EJ
影响因子：
6
作者：
Connolly, JM;Alferiev, I;Levy, RJ
通讯作者：
Levy, RJ