Computational fluid dynamics simulations in realistic 3-D geometries of the total cavopulmonary anastomosis: The influence of the inferior caval anastomosis
Computational fluid dynamics simulations in realistic 3-D geometries of the total cavopulmonary anastomosis: The influence of the inferior caval anastomosis
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DOI：
10.1115/1.1632523
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发表时间：
2003-12-01
影响因子：
1.7
通讯作者：
de Leval, MR
中科院分区：
文献类型：
--
作者：
Migliavacca, F;Dubini, G;de Leval, MR
利用磁共振（MR）图像获得的真实的尺寸，在三维模型中研究了全腔肺动脉连接（TCPC）的流体动力学。模型在下腔静脉（IVC）吻合连接的形状（心内或心外管道）和横截面（有或没有补片扩大）方面存在差异。真实的脉动流被提交到两个腔静脉，而多孔部分被添加在肺动脉的末端，以再现肺后负荷。计算不同肺小动脉阻力（PAR）值时的耗散功率和肺内流量分布。最重要的结果是：i）不同TCPC设计中的功耗受IVC吻合的实际横截面积影响，ii）包含贴片可最大限度地降低功耗（范围4-13 mW vs. 14-56 mW）。结果还表明，当PAR均匀分布在左右肺之间时，右肺的灌注占整个IVC血流的15%~ 30%。
Fluid dynamics of Total Cavo-Pulmonary Connection (TCPC) were studied in 3-D models based on real dimensions obtained by Magnetic Resonance (MR) images. Models differ in terms of shape (intra- or extra-cardiac conduit) and cross section (with or without patch enlargement) of the inferior caval (IVC) anastomosis connection. Realistic pulsatile flows were submitted to both the venae cavae, while porous portions were added at the end of the pulmonary arteries to reproduce the pulmonary afterload. The dissipated power and the flow distribution into the lungs were calculated at different values of pulmonary arteriolar resistances (PAR). The most important results are: i) power dissipation in different TCPC designs is influenced by the actual cross sectional area of the IVC anastomosis and ii) the inclusion of a patch minimizes the dissipated power (range 4-13 mW vs. 14-56 mW). Results also show that the perfusion of the right lung is between 15% and 30% of the whole IVC blood flow when the PAR are evenly distributed between the right and the left lung.