EFFECTS OF WAVELENGTH ON THE TIMING AND LAMINAR DISTRIBUTION OF ILLUMINANCE-EVOKED ACTIVITY IN MACAQUE V1
EFFECTS OF WAVELENGTH ON THE TIMING AND LAMINAR DISTRIBUTION OF ILLUMINANCE-EVOKED ACTIVITY IN MACAQUE V1
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DOI：
10.1017/s0952523800007914
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发表时间：
1995-03-01
影响因子：
1.9
通讯作者：
SCHROEDER, CE
中科院分区：
文献类型：
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作者：
GIVRE, SJ;AREZZO, JC;SCHROEDER, CE
对全场彩色闪光（红色，蓝色和绿色）的反应进行了比较，与亮度匹配的白色闪光在V1区，视辐射，和两个警觉猕猴的外侧膝状体核。层配置文件的视觉诱发电位（VEPs），电流源密度，和多单位的活动，获得使用多触点电极能够从所有层的皮层或外侧膝状体核，同时采样。在纹状皮质，彩色闪光刺激增强跨膜电流显着在层4c和颗粒上层。在每个电极穿透中，红色刺激引起最大增强。在4c层和颗粒上层，红光诱发的电流汇的平均峰值幅度分别是白色光诱发的电流汇的203%和537%。在V1的颜色效应之前，波长不敏感的活动的初始时期。在层4c中，红色效应平均在跨膜电流开始后47 ms或约24 ms达到显著性。在颗粒上层，红色效果达到显着性，平均在55毫秒，或近似14毫秒后，电流的开始。V1以下白色物质和外侧膝状体的光辐射记录显示，对颜色和亮度匹配的白色光的反应没有显着差异。用彩色刺激增强颗粒上电流增加了这些层对产生表面VEP的贡献。因此，比较由白色和彩色刺激引起的表面VEP波形可能有助于区分颗粒层和颗粒层上的反应。
Responses to full-field colored flashes (red, blue, and green) were compared with those to illuminance-matched white flashes in area V1, optic radiations, and the lateral geniculate nucleus of two alert macaques. Laminar profiles of visual evoked potentials (VEPs), current source density, and multiunit activity were obtained using multicontact electrodes capable of sampling from all layers of cortex or lateral geniculate nucleus, simultaneously. In striate cortex, stimulation with colored flash enhanced transmembrane current flow dramatically in both layer 4c and the supragranular laminae. Stimulation with red evoked the largest enhancement in every electrode penetration. The mean peak amplitudes of current sinks evoked by red were 203% and 537% of those evoked by white light in layer 4c and the supragranular laminae, respectively. Color effects in V1 were preceded by an initial epoch of wavelength-insensitive activity. In layer 4c, the red effect reached significance, on average, at 47 ms, or approximate to 24 ms after the onset of transmembrane current flow. In the supragranular layers, the red effect reached significance, on average, at 55 ms, or approximate to 14 ms after the onset of current flow. Recordings from optic radiations in the white matter below V1 and from lateral geniculate nucleus showed no significant difference in the responses to color and illuminance-matched white light. Enhancement of supragranular current flow with color stimulation increased the contribution of these laminae to the generation of the surface VEP. Comparison of the surface VEP wave forms evoked by white and color stimuli may, therefore, help to differentiate the responses of the granular and supragranular laminae.