Variable Time Normalization Analysis: General Graphical Elucidation of Reaction Orders from Concentration Profiles
Variable Time Normalization Analysis: General Graphical Elucidation of Reaction Orders from Concentration Profiles
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DOI：
10.1002/anie.201609757
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发表时间：
2016-12-23
影响因子：
16.6
通讯作者：
Bures, Jordi
中科院分区：
文献类型：
--
作者：
Bures, Jordi
反应监测技术的最新技术进展并没有被现代动力学分析的发展所取代。目前使用的分析忽略了所获得的部分数据，因此需要增加实验次数以获得给定化学反应的足够动力学信息。在这里，我们提出了一个简单的图形分析方法，利用现代反应监测工具提供的数据丰富的结果。该分析使用时间尺度的变量归一化，以实现整个浓度反应曲线的视觉比较。因此，反应的每个组分的顺序以及k（obs）仅通过几个实验使用简单快速的数学数据处理来确定。这种分析有利于快速提取相关的动力学信息，将是一个有价值的工具，为研究反应机理。
The recent technological evolution of reaction monitoring techniques has not been paralleled by the development of modern kinetic analyses. The analyses currently used disregard part of the data acquired, thus requiring an increased number of experiments to obtain sufficient kinetic information for a given chemical reaction. Herein, we present a simple graphical analysis method that takes advantage of the data-rich results provided by modern reaction monitoring tools. This analysis uses a variable normalization of the time scale to enable the visual comparison of entire concentration reaction profiles. As a result, the order in each component of the reaction, as well as k(obs), is determined with just a few experiments using a simple and quick mathematical data treatment. This analysis facilitates the rapid extraction of relevant kinetic information and will be a valuable tool for the study of reaction mechanisms.