ALTERATIONS IN THE IONIC COMPOSITION OF ISOTONIC SALINE SOLUTION INSTILLED INTO THE COLON
ALTERATIONS IN THE IONIC COMPOSITION OF ISOTONIC SALINE SOLUTION INSTILLED INTO THE COLON
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DOI：
10.1172/jci102757
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发表时间：
1953-01-01
影响因子：
15.9
通讯作者：
SCHWARTZ, WB
中科院分区：
文献类型：
--
作者：
DAGOSTINO, A;LEADBETTER, WF;SCHWARTZ, WB
在狗的离体结肠中注入等渗NaCl后，在结肠粘膜上建立梯度，其特征是高度关注。碳酸氢盐和低浓度的。结肠中的氯化物含量比血浆中的多。总阴离子浓度。基本保持不变。这种平衡的发展可能在输尿管肠造口术后高氯血症酸中毒的发生中起一定作用。用量。钠和钾在结肠壁上也有梯度。
Following instillation of isotonic NaCl into the isolated colon of the dog, gradients are established across the colonic mucosa characterized by a higher concn. of bicarbonate and lower concn. of chloride in the colon than in the plasma. Total anion concn. remains essentially unchanged. The development of this equilibrium probably plays a part in the genesis of hyperchloremic acidosis after ureteroenterostomy. Concn. gradients across the colonic wall are also established for Na and K.