Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system
Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system
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使用有缺陷且持久的仙台病毒载体系统生成对照人诱导多能干细胞系
DOI：
10.1016/j.scr.2021.102549
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发表时间：
2021
影响因子：
1.2
通讯作者：
Okano Hideyuki
中科院分区：
文献类型：
--
作者：
Zhou Zhi;Yoshimatsu Sho;Qian Emi;Ishikawa Mitsuru;Sato Tsukika;Ohtaka Manami;Nakanishi Mahito;Okano Hideyuki
有缺陷的和持久的仙台病毒（SeVdp）载体系统允许从人类体细胞有效产生无转基因的诱导多能干细胞（iPSC）。通过利用该系统，在此我们报告了从健康对照供体（雌性）的体细胞成纤维细胞产生iPSC系，命名为KEIOi 002-A（也命名为YG-iPS）。对照iPSC系将是干细胞研究和再生医学的有用资源。
The defective and persistent Sendai virus (SeVdp) vector system allows efficient generation of transgene-free induced pluripotent stem cells (iPSCs) from human somatic cells. By leveraging the system, here we report the generation of an iPSC line from somatic fibroblasts of a healthy control donner (female), named KEIOi002-A (also named YG-iPS). The control iPSC line would be a useful resource for stem cell research and regenerative medicine.