Cerebellar neoplasm of mixed mesenchymal and neuroepithelial origin. Case report.
Cerebellar neoplasm of mixed mesenchymal and neuroepithelial origin. Case report.
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混合间质和神经上皮起源的小脑肿瘤。
DOI：
10.3171/jns.1983.59.2.0337
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发表时间：
1983
影响因子：
4.1
通讯作者：
S. O'charoen
中科院分区：
文献类型：
--
作者：
S. Shuangshoti;S. O'charoen
一个3岁半的男孩有一个肿瘤的混合间充质和神经上皮起源的小脑蚓部。肿瘤由横纹肌肉瘤和髓母细胞瘤组成。在神经上皮细胞内有额外的分化，包括肿瘤性神经元、成神经细胞、星形胶质细胞、少突胶质细胞、室管膜细胞以及胶质母细胞瘤转化灶。提示该联合瘤起源于神经嵴或神经嵴与神经管的联合。横纹肌肉瘤可能起源于神经嵴的间叶部分，髓母细胞瘤可能起源于神经嵴的神经外胚层部分或神经管本身。这两种类型的肿瘤形成了一个肿瘤的混合间充质和神经上皮来源。
A 3 1/2-year-old boy had a neoplasm of mixed mesenchymal and neuroepithelial origin in the cerebellar vermis. The tumor was composed of rhabdomyosarcoma and medulloblastoma. There was additional differentiation within the neuroepithelium, including neoplastic neurons, neuroblasts, astroglia, oligodendroglia, ependymal cells as well as foci of glioblastomatous transformation. It is suggested that this combined tumor arose from the neural crest or combined neural crest and neural tube. The rhabdomyosarcoma could have arisen from the mesenchymal portion of the neural crest, and the medulloblastoma from the neuroectodermal part of the neural crest or from the neural tube itself. The two tumor types formed a neoplasm of mixed mesenchymal and neuroepithelial origin.