Progressive encephalopathy in children with chronic renal insufficiency in infancy.
Progressive encephalopathy in children with chronic renal insufficiency in infancy.
复制标题
婴儿期慢性肾功能不全儿童的进行性脑病。
DOI：
10.1038/ki.1982.50
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发表时间：
1982
影响因子：
19.6
通讯作者：
Michael,AF
中科院分区：
文献类型：
--
作者：
Rotundo,A;Nevins,TE;Lipton,M;Lockman,LA;Mauer,SM;Michael,AF
方法回顾性分析1岁以前诊断为慢性肾功能不全（CR 1）的儿童病历。试图包括1968年至1980年期间在明尼苏达大学医院看到的所有CR 1婴儿，但由于分析是回顾性的，一些患者，特别是那些病情较轻的患者，可能被忽略了。通过审查出院诊断为肾衰竭或肾功能不全的医院记录以及该期间儿科肾脏科、泌尿科和移植外科的记录来识别患者。出于本综述的目的，当神经系统检查显示被动运动阻力降低时，判定患者存在张力减退。使用丹佛发育筛查和贝利婴儿发育量表或斯坦福-比奈智力量表评估发育。症状或体征被认为是从第一次记录在患者病历中的时间开始存在的。
Methods Charts of children with a diagnosis of chronic renal insufficiency (CR1) established prior to 1 year of age were reviewed. Attempts were made to include all infants with CR1 seen at the University of Minnesota Hospitals during the period 1968 to 1980, but because the analysis was retrospective, some pa-tients, especially those with less severe disease, may have been overlooked. Patients were identified by reviewing hospital records with a discharge diagnosis of renal failure or renal insufficiency, as well as records from the Divisions of Pediatric Nephrology, Urology, and Transplant Surgery for this period. For the purposes of this review, hypotonia was judged to be present in patients when the neurological exam revealed a decreased resistance to passive movement. Development was assessed using the Denver Developmental Screen and either the Bayley Scales of Infant Development or the Stanford-Binet Intelligence Scale. A symptom or sign was considered to be present from the time it was first documented in the patient's chart.