THE ECOLOGY OF CRYPTOCOCCUS NEOFORMANS

THE ECOLOGY OF CRYPTOCOCCUS NEOFORMANS
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DOI:
10.1007/bf00158562
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发表时间:
1992-05-01
影响因子:
13.6
通讯作者:
PFEIFFER, T
PFEIFFER, T
中科院分区:
医学1区
文献类型:
--
作者:
ELLIS, D;PFEIFFER, T

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环境隔离已确定,新型隐球菌变种。gattii血清型B似乎与赤桉具有特定的生态关联。该树的全球分布似乎与隐球菌病的流行病学分布相对应。新形变种加提。隐球菌病的流行病学主要可以解释为暴露于感染性气溶胶接种物,如从特定宿主植物释放的担孢子和/或从干燥鸽粪积累物传播的干燥芽生孢子(酵母细胞)。对C.新形虫的感染仍在很大程度上未解决,血清型B和E之间宿主-寄生虫相互作用的研究。Camaldulensis的研究仍在进行中,目前正在进行广泛的环境搜索,以确定血清型A、C和D的自然栖息地。
Environmental isolations have established that Cryptococcus neoformans var. gattii serotype B appears to have a specific ecological association with Eucalyptus camaldulensis. The global distribution of the tree appears to correspond to the epidemiologic distribution of cryptococcosis caused by C. neoformans var. gattii. The epidemiology of cryptococcosis can primarily be explained by exposure to an infective aerosolized inoculum, such as basidiospores released from specific host plants and/or desiccated blastoconidia (yeast cells) disseminated from accumulations of dried pigeon dung. The ecology of C. neoformans still remains largely unresolved, studies on the host-parasite interaction between serotype B and E. camaldulensis are still in progress, and extensive environmental searches are now underway to determine the natural habitats of serotypes A, C and D.