Fabrication of Porous Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Monoliths via Thermally Induced Phase Separation
Fabrication of Porous Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Monoliths via Thermally Induced Phase Separation
复制标题
DOI：
10.3390/polym8030066
复制
发表时间：
2016-02
期刊：
影响因子：
5
通讯作者：
T. Tsujimoto;N. Hosoda;H. Uyama
中科院分区：
文献类型：
--
作者：
T. Tsujimoto;N. Hosoda;H. Uyama
本研究以细菌聚酯为原料，通过热致相分离法制备生物可降解多孔材料，即聚（3-羟基丁酸酯-co-3-羟基己酸酯）（P3 HB 3 HHx）。具有拓扑多孔结构的P3 HB 3 HHx整料通过在85 °C下将P3 HB 3 HHx溶解在二甲基亚砜（DMSO）中并随后淬灭来制备。所得P3 HB 3 HHx整料的微观结构通过聚合物溶液的P3 HB 3 HHx浓度而改变。差示扫描量热法和偏光显微镜分析表明，在相分离和随后的老化过程中的P3 HB 3 HHx整料结晶。力学性能，如压缩模量和应力，整料依赖于3-羟基己酸含量的P3 HB 3 HHx。此外，在植物油-水混合物中，P3 HB 3 HHx整料优先吸收亚麻籽油而不是水。结合P3 HB 3 HHx的生物降解特性，本研究有望为生物基材料的开发做出贡献。
This study deals with the fabrication of biodegradable porous materials from bacterial polyester, poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P3HB3HHx), via thermally induced phase separation. P3HB3HHx monoliths with topological porous structure were prepared by dissolution of P3HB3HHx in dimethyl sulfoxide (DMSO) at 85 °C and subsequent quenching. The microstructure of the resulting P3HB3HHx monoliths was changed by the P3HB3HHx concentration of the polymer solution. Differential scanning calorimetry and polarized optical microscope analysis revealed that the P3HB3HHx monoliths crystallized during phase separation and the subsequent aging. The mechanical properties, such as compression modulus and stress, of the monoliths depended on the 3-hydroxyhexanoate content of P3HB3HHx. Furthermore, the P3HB3HHx monolith absorbed linseed oil in preference to water in a plant oil–water mixture. In combination with the biodegradable character of P3HB3HHx, the present study is expected to contribute to the development of bio-based materials.