Transthyretin gene (TTR) intron 1 elucidates crocodylian phylogenetic relationships.
Transthyretin gene (TTR) intron 1 elucidates crocodylian phylogenetic relationships.
复制标题
运甲状腺素蛋白基因 (TTR) 内含子 1 阐明了鳄鱼的系统发育关系。
DOI：
10.1016/j.ympev.2009.09.003
复制
发表时间：
2009
影响因子：
4.1
通讯作者：
Willis,RayE
中科院分区：
文献类型：
--
作者：
Willis,RayE
Transthyretin (TTR) is an attractive candidate for use in phylogenetic analysis because it is a short, single-copy nuclear gene with regions that are highly conserved across evolutionarily-divergent organisms from Xenopus laevis to Homo sapiens. To explore its utility as a phylogenetic marker, the complete intron one region (789–805 bp) was sequenced in 22 crocodylian species. Detailed analyses of intron 1 resolved the three expected lineages, Alligatorids, Crocodylids, and Gavialids, and offered additional evidence for the utility of synapomorphic indels in elucidating higher-level phylogenetic relationships. When used in conjunction with other genetic and morphological data sets, intron 1 should be a valuable tool in the investigation of other closely related taxa.
