Memory performance in Holocaust survivors with posttraumatic stress disorder
Memory performance in Holocaust survivors with posttraumatic stress disorder
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DOI：
10.1176/appi.ajp.159.10.1682
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发表时间：
2002-10-01
影响因子：
17.7
通讯作者：
Elkin, A
中科院分区：
文献类型：
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作者：
Golier, JA;Yehuda, R;Elkin, A
目的：作者评估了大屠杀幸存者的记忆表现及其与创伤后应激障碍（PTSD）和age.Method的关联：记忆表现在大屠杀幸存者与PTSD（N= 31）和没有PTSD（N=16）和健康的犹太成年人没有暴露于大屠杀（N=35）。显式和内隐记忆分别测量配对联想回忆和词干completen.Results：各组没有不同的年龄或性别，但创伤后应激障碍的幸存者有显着较少的教育年数，并有较低的估计智商比幸存者没有创伤后应激障碍和nonexposed组。有一个显着的整体组效应配对联想回忆，但没有词干完成。PTSD幸存者回忆起的语义无关的单词比没有PTSD的幸存者和非暴露组少，语义相关的单词比非暴露组少。在PTSD幸存者中，36%的人表现出明显的认知障碍。年龄较大的显着相关性较差的配对联想回忆的幸存者与PTSD，但不是在其他两个groups.Conclusions：显着较差的外显记忆，但不是内隐记忆被发现在大屠杀幸存者与PTSD，这可能是慢性PTSD的后果或危险因素。加速记忆衰退是PTSD幸存者中年龄较大与外显记忆较差显著相关的几种解释之一，如果存在，可能会增加这种疾病的认知负担。
Objective: The authors evaluated memory performance in Holocaust survivors and its association with posttraumatic stress disorder (PTSD) and age.Method: Memory performance was measured in Holocaust survivors with PTSD (N= 31) and without PTSD (N=16) and healthy Jewish adults not exposed to the Holocaust (N=35). Explicit and implicit memory were measured by paired-associate recall and word stem completion, respectively.Results: The groups did not differ by age or gender, but the survivors with PTSD had significantly fewer years of education and had lower estimated IQs than the survivors without PTSD and the nonexposed group. There was a significant overall group effect for paired-associate recall but not word stem completion. The survivors with PTSD recalled fewer semantically unrelated words than did the survivors without PTSD and the nonexposed group and fewer semantically related words than the nonexposed group. Of the survivors with PTSD, 36% performed at a level indicative of frank cognitive impairment. older age was significantly associated with poorer paired-associate recall in the survivors with PTSD but not in the other two groups.Conclusions: Markedly poorer explicit but not implicit memory was found in Holocaust survivors with PTSD, which may be a consequence of or a risk factor for chronic PTSD. Accelerated memory decline is one of several explanations for the significantly greater association of older age with poorer explicit memory in survivors with PTSD, which, if present, could increase the cognitive burden of this illness with aging.