THE SUPRACHIASMATIC NUCLEI STIMULATE EVENING ACTH-SECRETION IN THE RAT
THE SUPRACHIASMATIC NUCLEI STIMULATE EVENING ACTH-SECRETION IN THE RAT
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DOI：
10.1016/0006-8993(87)90837-7
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发表时间：
1987-10-13
期刊：
影响因子：
2.9
通讯作者：
DALLMAN, MF
中科院分区：
文献类型：
--
作者：
CASCIO, CS;SHINSAKO, J;DALLMAN, MF
研究了双侧视交叉上核（SCN）病变对ACTH昼夜节律的影响，这些大鼠肾上腺切除并皮下植入皮质酮(B)颗粒。大鼠长期插管，以便重复采血。在服用B颗粒的大鼠中，双侧SCN病变消除了假损伤动物中血浆ACTH的昼夜升高。这与SCN在晚上刺激ACTH分泌的观点是一致的。
The effect of bilateral lesions of the suprachiasmatic nuclei (SCN) on the circadian rhythm in ACTH was studied in rats that were adrenalectomized and implanted with a subcutaneous corticosterone (B) pellet. Rats were chronically cannulated to allow for repeated blood sampling. In rats with B pellets, bilateral lesions of the SCN eliminated the circadian rise in plasma ACTH seen in sham-lesioned animals. This is consistent with the idea that the SCN stimulate ACTH secretion in the evening.