Parallel combinatorial synthesis of Azo dyes - A combinatorial experiment suitable for undergraduate laboratories
Parallel combinatorial synthesis of Azo dyes - A combinatorial experiment suitable for undergraduate laboratories
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DOI：
10.1021/ed081p1630
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发表时间：
2004-11-01
影响因子：
3
通讯作者：
Taylor, RT
中科院分区：
文献类型：
--
作者：
Gung, BW;Taylor, RT
发展了一个平行组合合成偶氮染料的实验，该实验使用不同的颜色来说明多样性和结构-功能关系的概念。本实验适合于本科生实验室使用，并已在迈阿密大学化学专业和非化学专业本科生中使用。偶氮染料可以很容易地在一个实验室周期内制备，并被选择来说明多样性导向合成的概念。在实验中，实验室的位置被划分成一个网格。每个学生产生一个独特的偶氮染料，其结构是根据他或她的实验室工作台的位置编码。在实验结束时，用学生自己的合成染料染色一条多纤维带。一个色彩斑斓的光谱是偶氮类染料集体产生的。
A parallel combinatorial synthesis of azo dyes experiment was developed that uses distinct colors to illustrate the concept of diversity and structure–function relationships. This experiment is suitable for undergraduate laboratories and has been used by both chemistry majors and nonmajors undergraduates in Miami University. Azo dyes can be prepared easily in one laboratory period and were chosen to illustrate the concept of diversity oriented synthesis. In the experiment, the positions of the laboratory are divided into a grid. Each student produces a unique azo dye, whose structure is coded according to his or her lab bench position. At the end of the experiment, a multifiber strip is dyed using the student's own synthetic dye. A colorful spectrum of azo dyes are produced collectively by the class.