A miniature fiber optic surface plasmon resonance sensor for fast detection of staphylococcal enterotoxin B
A miniature fiber optic surface plasmon resonance sensor for fast detection of staphylococcal enterotoxin B
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DOI：
10.1016/s0956-5663(02)00013-1
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发表时间：
2002-06-01
影响因子：
12.6
通讯作者：
Brynda, E
中科院分区：
文献类型：
--
作者：
Slavík, R;Homola, J;Brynda, E
报道了一种检测葡萄球菌肠毒素B（SE B）的光纤表面等离子体共振（SPR）生物传感器。该传感器的基础上，在一个微型传感元件的基础上侧抛光的单模光纤与薄金属覆盖层的表面等离子体的光谱询问。对于SEB的特异性检测，SPR传感器用针对SEB的抗体的共价交联双层功能化。SPR生物传感器被证明能够在不到10分钟的时间内检测到ng/ml浓度的SEB。（C）2002 Elsevier Science B. V.保留所有权利。
A fiber optic surface plasmon resonance (SPR) biosensor for detection of Staphylococcal enterotoxin B (SEB) is reported. The sensor is based on spectral interrogation of surface plasmons in a miniature sensing element based on a side-polished single-mode optical fiber with a thin metal overlayer. For specific detection of SEB, the SPR sensor is functionalized with a covalently crosslinked double-layer of antibodies against SEB. The SPR biosensor is demonstrated to be able to detect ng/ml concentrations of SEB in less than 10 min. (C) 2002 Elsevier Science B.V. All rights reserved.