Receiver operating characteristic analysis of sphincter electromyography for parkinsonian syndrome
Receiver operating characteristic analysis of sphincter electromyography for parkinsonian syndrome
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DOI：
10.1002/nau.22208
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发表时间：
2012-09-01
影响因子：
2
通讯作者：
Kuwabara, Satoshi
中科院分区：
文献类型：
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作者：
Yamamoto, Tatsuya;Sakakibara, Ryuji;Kuwabara, Satoshi
目的：我们进行受试者工作特征（ROC）分析，以确定括约肌肌电图（EMG）区分多系统萎缩（MSA）与其他帕金森病的能力。(1)确定持续时间、相、幅之间合适的运动单位电位（MUP）参数；(2)我们的持续时间标准的理想参数；也就是说，超过20%的mup拥有bb10 ？Ms持续时间（标准a）或平均持续时间bbb10 ？Ms（标准b）。方法回顾性分析441例帕金森综合征患者的括约肌肌电图：MSA， n?=?263；帕金森病，n?=?129；路易体痴呆，n?=?25；进行性核上性麻痹，n?=?24。我们对数据集进行ROC分析。结果用于区分MSA与其他帕金森综合征的曲线下面积分别为0.68、0.57和0.51；这些值具有统计学意义。关于我们的持续时间标准，mup的平均持续时间（标准b）的曲线下面积为0.69，mup持续时间bbbb10的百分比为0.67 ？Ms（准则a）；这些数值也具有统计学意义。结论持续时间是判断MSA分化的合适指标。然而，平均持续时间曲线下面积不足以确定诊断；括约肌肌电图可作为MSA诊断的辅助诊断工具。Neurourol。生物力学学报。31:11281134,2012。(c) 2012 Wiley期刊有限公司
Aims We performed receiver operating characteristic (ROC) analysis to determine the ability of sphincter electromyography (EMG) to distinguish multiple system atrophy (MSA) from other parkinsonisms. The following was determined: (1) the appropriate motor unit potential (MUP) parameter among duration, phase, and amplitude; (2) the desirable parameter of our duration criteria; that is, more than 20% MUPs having >10?ms duration (criteria a) or mean duration >10?ms (criteria b). Methods We retrospectively reviewed 441 case records where sphincter EMG were performed in patients with parkinsonian syndromes: MSA, n?=?263; Parkinson's disease, n?=?129; dementia with Lewy bodies, n?=?25; and progressive supranuclear palsy, n?=?24. We performed ROC analysis of the data sets. Results The area under the curve used to differentiate MSA from other parkinsonian syndromes was 0.68 in duration, 0.57 in phase, and 0.51 in amplitude, respectively; these values were statistically significant. With regard to our duration criteria, area under the curve was 0.69 for the average duration of MUPs (criteria b) and 0.67 for percentage of MUPs of duration >10?ms (criteria a); these values were also statistically significant. Conclusions This study suggests that duration is appropriate parameter for the differentiation of MSA. However, the area under the curve of the mean duration was insufficient to confirm the diagnosis; sphincter EMG should be used as a supportive diagnostic tool for the diagnosis of MSA. Neurourol. Urodynam. 31:11281134, 2012. (c) 2012 Wiley Periodicals, Inc.