Neuronal morphogenesis: Golgi outposts, acentrosomal microtubule nucleation, and dendritic branching.
Neuronal morphogenesis: Golgi outposts, acentrosomal microtubule nucleation, and dendritic branching.
复制标题
神经元形态发生:高尔基体前哨、中心体微管成核和树突分支。
DOI:
10.1016/j.neuron.2012.11.019
复制
发表时间:
2012
期刊:
影响因子:
16.2
通讯作者:
Polleux,Franck
中科院分区:
文献类型:
--
作者:
LewisJr,TommyL;Polleux,Franck
In large cells like neurons, how is microtubule polymerization initiated at large distances from the cell body and the main microtubule-organizing center? In this issue ofNeuron, Ori-McKenney et al. (2012) demonstrate that Golgi outposts mediate acentrosomal microtubule nucleation and reveal it is crucial for dendrite morphogenesis.