Design of axially chiral dicarboxylic acid for asymmetric Mannich reaction of arylaldehyde N-Boc imines and diazo compounds
Design of axially chiral dicarboxylic acid for asymmetric Mannich reaction of arylaldehyde N-Boc imines and diazo compounds
复制标题
DOI：
10.1021/ja0713375
复制
发表时间：
2007-08-22
影响因子：
15
通讯作者：
Maruoka, Keiji
中科院分区：
文献类型：
--
作者：
Hashimoto, Takuya;Maruoka, Keiji
制备了一种轴向手性二羧酸作为一类新型手性氢键催化剂，并将其应用于芳醛N-Boc亚胺和重氮化合物的高对映选择性Mannich反应。
An axially chiral dicarboxylic acid has been prepared as a new class of chiral hydrogen-bonding catalysts and applied to the highly enantioselective Mannich reaction of arylaldehyde N-Boc imines and diazo compounds.