Quality of life, diagnosis, and treatment of patients with major depression: a prospective cohort study in primary care
Quality of life, diagnosis, and treatment of patients with major depression: a prospective cohort study in primary care
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DOI：
10.1590/s1516-44462011000300007
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发表时间：
2011-09-01
影响因子：
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通讯作者：
Fleck, Marcelo Pio de Almeida
中科院分区：
文献类型：
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作者：
Lima, Ana Flávia Barros da Silva;Fleck, Marcelo Pio de Almeida
目的：描述接受初级保健中心随访治疗的重性抑郁症患者的人口统计学和临床特征、抗抑郁治疗的充分性以及生活质量的变化。方法：进行了一项队列研究，其中抑郁症患者随访超过9个月。使用了几种评估工具，包括世界卫生组织的生活质量和生活质量抑郁症，流行病学中心抑郁症问卷。结果：样本包括179人，大多数是女性（73%），平均年龄为38岁，平均教育9年。在随访期结束时，42%的人仍然患有重度抑郁症，25%的人症状完全缓解，只有9%的人接受了适当的抗抑郁药治疗。在生活质量方面，几乎所有指标都存在显著差异，尤其是基线和9个月后。结论：这项研究表明，抑郁症状认识不足，治疗往往是不够的，在巴西南部的初级保健单位随访的患者。大多数患者在9个月的时间里继续出现抑郁症状，这与生活质量受损有关。
Objective: To describe the demographic and clinical characteristics, adequacy of antidepressant treatment, and changes in quality of life of patients with major depression receiving follow-up care from primary care centers. Method: A cohort study was performed in which major depression patients were followed-up over a nine-month period. Several evaluation instruments were used, including the World Health Organization Quality of Life and the Quality of Life-Depression, Centers for Epidemiologic Studies-Depression questionnaires. Results: The sample comprised 179 individuals, mostly female (73%), with a mean age of 38 years and mean education of 9 years. At the end of the follow-up period, 42% of the individuals still presented with major depression, 25% had complete symptom remission, and only 9% were properly treated with antidepressants. In relation to quality of life, there were significant differences especially between baseline and after nine months in almost all measures. Conclusion: This study demonstrated that depressive symptoms are poorly recognized and that treatment is often inadequate for patients followed-up in primary care units in the south of Brazil. Most of the patients continued to have symptoms of depression over the nine-month period which were associated with impaired quality of life.