Regeneration of organized epithelial structure.
Regeneration of organized epithelial structure.
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有组织的上皮结构的再生。
DOI：
10.1111/1523-1747.ep12541093
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Fusenig,NE
中科院分区：
文献类型：
--
作者：
Mackenzie,IC;Fusenig,NE
结缔组织在成年期促进和指导上皮细胞生长的作用尚不确定。与维护上皮结构和以前的工作有关的作用，间充质在这个过程中的胚胎和成人的基本过程进行了审查。描述了一系列实验，其检查结缔组织在体外和体内移植后促进上皮生长和发育中的作用。这些实验证实了如果要重建正常结构，需要真皮成分，并指出需要真皮而不是深层结缔组织来促进体内成年上皮的生长，体外实验表明存在促进上皮生长的可扩散的真皮产生的因子。
The role of connective tissue in facilitating and directing the growth of epithelia during adult life is uncertain. The basic processes associated with maintenance of epithelial structure and previous work concerning the role of mesenchyme in this process in the embryo and adult are reviewed. A series of experiments examining the role of connective tissue in facilitating epithelial growth and development in vitro and after transplantation in vivo is described, These confirm the requirement for dermal elements if normal structure is to be reestablished and point to the requirement of dermal, as opposed to deep, connective tissues for facilitation of the growth of adult epithelia in vivo, The in vitro experiments suggest the presence of diffusible dermally produced factors that facilitate epithelial growth.