Large Syncytia in Lymph Nodes Induced by CCR5-Tropic HIV-1.
Large Syncytia in Lymph Nodes Induced by CCR5-Tropic HIV-1.
复制标题
CCR5-Tropic HIV-1 诱导淋巴结中的大合胞体。
DOI:
10.1089/aid.2014.0378
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发表时间:
2015
影响因子:
1.5
通讯作者:
Mempel,ThorstenR
中科院分区:
文献类型:
--
作者:
Murooka,ThomasT;Sharaf,RadwaR;Mempel,ThorstenR
FIG. 1. Large syncytium with multiple dendritic extensions in the lymph node of a BLT humanized NOD-SCID mice. The footpad was injected with 1· 105 IU of HIV-GFP and the draining popliteal lymph node was prepared for intravital microscopy at day 6 postinfection. The micrograph of HIV-infected cells (EGFP+; green) is a maximum intensity projection of 11 z-stacks, spaced 4 lm apart (total thickness of 40 lm). Red-orange objects are autofluorescent tissue structures. Scale bar= 60 lm.