DIRECT VISUALIZATION OF THE DENDRITIC AND RECEPTIVE-FIELDS OF DIRECTIONALLY SELECTIVE RETINAL GANGLION-CELLS
DIRECT VISUALIZATION OF THE DENDRITIC AND RECEPTIVE-FIELDS OF DIRECTIONALLY SELECTIVE RETINAL GANGLION-CELLS
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DOI：
10.1126/science.1470920
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发表时间：
1992-12-18
期刊：
影响因子：
56.9
通讯作者：
MASLAND, RH
中科院分区：
文献类型：
--
作者：
YANG, G;MASLAND, RH
用光学方法对离体兔视网膜定向选择性神经节细胞胞体进行定位。这些神经元检测图像在视网膜表面移动的方向，并将该信息传输到大脑。测定每个鉴定的细胞的感受野，之后向细胞注射荧光黄。然后将感受野边界的图像投射到树突的荧光图像上，从而可以进行精确的比较。感受野的大小与该细胞的树枝状结构的大小密切匹配。这一结果限制了可以在视网膜方向选择性机制建模中假设的会聚类型。
Optical methods were used to locate the cell bodies of directionally selective ganglion cells in isolated rabbit retinas. These neurons detect the direction in which images move across the retinal surface and transmit that information to the brain. The receptive field of each identified cell was determined, after which the cell was injected with Lucifer yellow. An image of the receptive field border was then projected onto the fluorescent image of the dendrites, allowing precise comparison between them. The size of the receptive field matched closely the size of the dendritic arbor of that cell. This result restricts the types of convergence that can be postulated in modeling the mechanism of retinal directional selectivity.