Strategy to Attain Remarkably High Photoinduced Charge-Separation Yield of Donor-Acceptor Linked Molecules in Biological Environment via Modulating Their Cationic Moieties
Strategy to Attain Remarkably High Photoinduced Charge-Separation Yield of Donor-Acceptor Linked Molecules in Biological Environment via Modulating Their Cationic Moieties
复制标题
通过调节阳离子部分在生物环境中获得供体-受体连接分子的极高光致电荷分离产率的策略
DOI：
10.1021/acs.jpcc.7b04466
复制
发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
and H. Imahori
中科院分区：
文献类型：
--
作者：
N. Cai;Y. Takano;T. Numata;R. Inoue;Y. Mori;T. Murakami;and H. Imahori
设计并制备了一系列具有不同数量阳离子部分的二茂铁-卟啉-富勒烯连接三联体（TC1、TC2和TC4），以在生物环境中实现高光致电荷分离（CS）产率。在溶液中，TC1、TC2 和 TC4 展示了其纳米聚集体的形成。在新的三联体中，具有四个阳离子部分的TC4表现出长寿命的电荷分离状态的形成，在细胞膜样脂质双层中具有最高的CS产率（86％），这与绿光照射下光诱导CS引起的PC12细胞细胞膜电位的最大变化一致。生物环境中最高的CS产率可以通过TC4的疏水性和亲水性的精心设计的平衡来合理化。这一发现提供了一种大大提高生物环境中供体-受体连接分子的光致电荷分离产率的策略，并且也将为充分发挥光致电荷分离状态在生物应用中的潜力提供信息。
A series of ferrocene–porphyrin–fullerene linked triads (TC1,TC2, andTC4) possessing different numbers of cationic moieties were designed and prepared to achieve a high photoinduced charge-separation (CS) yield in a biological environment. In a solution,TC1,TC2, andTC4demonstrated the formation of their nanoaggregates. Among the new triads,TC4possessing the four cationic moieties exhibited the formation of a long-lived charge-separated state with the highest CS yield (86%) ever reported in cell membrane-like lipid bilayers, which is consistent with the largest change in the cell membrane potential of PC12 cells via the photoinduced CS under green light illumination. The highest CS yield in the biological environment can be rationalized by the well-tailored balance in hydrophobicity and hydrophilicity ofTC4. This finding provides a strategy to improve greatly the photoinduced charge-separation yield of donor–acceptor linked molecules in the biological environment and also will be informative for extracting the full potential of the photoinduced charge-separated state toward biological applications.