Frequent analgesic use at population level:: Prevalence and patterns of use
Frequent analgesic use at population level:: Prevalence and patterns of use
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DOI：
10.1016/j.pain.2005.03.013
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发表时间：
2005-06-01
期刊：
影响因子：
7.4
通讯作者：
Ahonen, RS
中科院分区：
文献类型：
--
作者：
Turunen, JHO;Mäntyselkä, PT;Ahonen, RS
统计数据和处方数据库研究表明，镇痛药被广泛使用，但没有告诉任何关于镇痛药使用背后的因素或如何使用非处方（OTC）镇痛药。我们的目的是研究处方镇痛药和非处方镇痛药的频繁使用情况。我们还调查了与频繁使用镇痛药相关的背景因素，并评估了镇痛药使用模式的合理性。我们对6500名年龄在15-74岁之间的芬兰随机分层人口样本进行了邮政调查。排除无法获得的地址（n =68）后，回复率为71% （n = 4542）。报告“每天”或“每周几次”使用镇痛药的人被归类为频繁使用者。在调整了年龄和性别后，每日使用镇痛药的总体患病率为8.5%。而每周使用几次镇痛药的患病率为13.6%。每日或每周使用几次处方镇痛药的调整患病率为8.7%，使用纯OTC镇痛药的调整患病率为8.8%。同时频繁使用处方镇痛药和非处方镇痛药的总体患病率为4.6%。多项逻辑回归分析显示，频繁使用镇痛药尤其与每日或持续疼痛和高疼痛强度有关。情绪低落和不工作也增加了每天使用止痛药的可能性。在人群中，频繁使用止痛药似乎是很常见的。同时使用处方和非处方镇痛药可被认为是不合理的，因为它增加了不良事件的风险。(c) 2005年国际疼痛研究协会。Elsevier b.v.出版，版权所有。
Statistics and prescription database studies show that analgesics are widely utilized, but do not tell anything about either (lie factors behind analgesic use or how over-the-counter (OTC) analgesics are being used. We aimed to study (lie prevalence of frequent use of prescribed and OTC analgesics. We also investigated the background factors related to frequent analgesic use and assessed rationality of analgesic usage patterns. We addressed a postal survey to a random stratified population sample of 6500 Finnish people aged 15-74 years. The response rate was 71% (n = 4542) after exclusion of unobtainable addressees (n =68). Individuals reporting analgesic use 'daily' or 'a few times a week' were categorized as frequent users. After adjusting for age and sex, the overall prevalence of daily analgesics use was 8.5%. and the prevalence of analgesic use a few times a week 13.6%. The adjusted prevalence of using exclusively prescribed analgesics daily or a few times a week was 8.7%, and that of utilizing purely OTC analgesics 8.8%. The overall prevalence of Concomitant frequent use of both prescribed and OTC analgesics was 4.6%. Multinominal logistic regression analyses showed that frequent analgesic use was related especially to daily or continuous pain and high pain intensity. Low mood and not being employed also increased the probability for daily analgesic use. Frequent analgesic use seems to be common at population level. Concomitant use of both prescribed and OTC analgesics can be considered irrational, as it increases the risk of adverse events. (c) 2005 International Association for the Study of Pain. Published by Elsevier B.V, All rights reserved.