Clinical significance of bacteremia involving the "Streptococcus milleri" group:: 51 cases and review

Clinical significance of bacteremia involving the "Streptococcus milleri" group:: 51 cases and review
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DOI:
10.1086/514658
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发表时间:
1998-08-01
影响因子:
11.8
通讯作者:
Lambert-Zechovsky, N
Lambert-Zechovsky, N
中科院分区:
医学1区
文献类型:
--
作者:
Bert, F;Bariou-Lancelin, M;Lambert-Zechovsky, N

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本文分析了51例由“米勒链球菌”群引起的菌血症。其中40例患者有基础疾病,27例患者存在相关的局部感染。最常见的感染部位是胸腔、消化道和肝胆道。另外16例患者确定了与粘膜屏障损伤相关的可能入口。其余8例患者的菌血症起源不明。只有6名患者明显形成脓肿,没有心内膜炎病例。多重阳性血培养和多菌血症与局部感染部位的存在显著相关。最常见的致病菌是咽峡炎链球菌和星座链球菌。2例患者死于菌血症。
Fifty-one cases of bacteremia due to the "Streptococcus milleri" group were analyzed. Among these were 40 patients with underlying diseases, and associated local infections were present in 27 patients. The most frequent sites of infection were the thoracic cavity and the digestive and hepatobiliary tracts. A probable portal of entry related to mucosal-barrier trauma was identified for an additional 16 patients. The origin of bacteremia was unknown for the remaining eight patients. Abscess formation was evident for only six patients, and there were no cases of endocarditis. Multiple positive blood cultures and polymicrobial bacteremia were associated significantly with the presence of local sites of infection. The most common causative species were Streptococcus anginosus and Streptococcus constellatus. Two patients died of bacteremia.