Direct Quantitative Analysis of Fluorine in Solid Samples by Cryogenic Laser Ablation and Ionization Time-of-Flight Mass Spectrometry
Direct Quantitative Analysis of Fluorine in Solid Samples by Cryogenic Laser Ablation and Ionization Time-of-Flight Mass Spectrometry
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通过低温激光烧蚀和电离飞行时间质谱法直接定量分析固体样品中的氟
DOI：
10.1021/acs.analchem.2c04372
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发表时间：
2022
影响因子：
7.4
通讯作者：
Wei Hang
中科院分区：
文献类型：
--
作者：
Zhenjian Zhang;Siyuan Ma;Le Hang;Zhouyi Xu;Wei Hang
氟是卤素中最轻的元素，在质谱分析中，氟的测定会受到高电离势和水分子的光谱干扰。在此，我们首次将液氮冷却单元引入激光烧蚀电离源中，构建了低温激光烧蚀电离飞行时间质谱（Cryo-LAI-TOFMS）系统。该系统有效消除了与水有关的物种atm/z19的干扰，氟雾化电离效率可达6.3%。开发了一种直接定量分析方法来测定磷矿、铜矿石、工业副产石膏、河流沉积物和土壤中的氟含量。考虑到该技术简单、灵敏度高、光谱干扰低等特点，可推广至复杂固体样品中低至μg/g氟含量的测定。
The determination of fluorine, the lightest element in halogens, suffers from high ionization potential and spectral interference from water molecules in mass spectrometry. Herein, we introduced a liquid nitrogen cooling unit into the laser ablation and ionization source for the first time to construct a cryogenic laser ablation and ionization time-of-flight mass spectrometry (Cryo-LAI-TOFMS) system. With this system, the interference of water-related species atm/z19 was effectively eliminated, and fluorine atomization and ionization efficiency could reach 6.3%. A direct quantitative analysis method was developed to determine fluorine contents in phosphate rock, copper ore, industrial byproduct gypsum, stream sediment, and soil. Considering the simplicity, high sensitivity, and low spectral interference of this technique, it can be extended to the determination of fluorine content as low as μg/g in complex solid samples.